MantisBT - MEGA
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IDProjectCategoryView StatusDate SubmittedLast Update
0006859MEGA[All Projects] Feedbackpublic2025-10-13 05:102025-10-13 05:10
Reporterguest 
Assigned To 
PrioritynormalSeverityminorReproducibilityhave not tried
StatusnewResolutionopen 
PlatformOSOS Version
Product VersionMEGA 12 
Target VersionFixed in Version 
First NameThomas
Last NameKuyper
Emailthom.kuyper@wur.nl
Confirm Emailthom.kuyper@wur.nl
Summary0006859: bootstrap values
DescriptionMEGA12 gives much higher bootstrap values than MEGA 11. I tested both versions with a data set of 600 nucleotides with two taxa (each five identical sequences) that differ in 1 nucleotide only. Bootstrapping with MEGA 11 gives a bootstrap value of 60-65%, MEGA 12 values of consistently 100%. With an alignment of 600 nucleotides (columns) the chances that one nucleotide (column) will be present in the resampled alignment with replacement equals

1 – [(x-1)expt(x)/(x)expt(x)]

= 63%

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2025-10-13 05:10guestNew Issue

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